Best for Persistent Flakes

Nizoral Anti-Dandruff Shampoo (Ketoconazole 1%)

An OTC ketoconazole shampoo that many people reach for when gentler anti-flake washes aren't enough — used twice weekly per the label. For persistent symptoms, see a dermatologist.

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  • Active Ketoconazole 1%
  • Use 2x/week per label
  • Note Follow package directions

Specifications

Active Ketoconazole 1%
Use 2x/week per label
Note Follow package directions

Pros and cons

What we like

  • Active ketoconazole 1%
  • Used just twice a week
  • Widely recommended for stubborn flakes

What we don't

  • Can be drying
  • Medicinal, not a daily shampoo

Nizoral is the OTC anti-dandruff shampoo people turn to when lighter formulas fall short: its active ingredient is ketoconazole 1%, used about twice a week per the label. Follow the package directions, alternate with a gentle shampoo since it can be drying, and see a dermatologist for persistent or severe symptoms. Informational, not medical advice.

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Nizoral Anti-Dandruff Shampoo (Ketoconazole 1%)